专利名称:Method and computer program product for
assessing neurological conditions andtreatments using evoked responsepotentials
发明人:Richard Granger申请号:US09773732申请日:20010202公开号:US06463321B2公开日:20021008
专利附图:
摘要:A method is provided for diagnosing the presence of a neurological disorder or
otherwise assessing the neurological condition of a patient. The method also allows theassessment of a treatment regimen used by a patient. The method includes the
collection and analysis of ERP data. The method of the invention begins by conducting aplurality of ERP trials on a patient. In an embodiment of the invention, the data from theERP trials is then characterized to produce a characterizing ERP signal vector for thepatient. Projections based on the characterizing ERP signal vector are then generated.The projections are compared to information derived from the ERP data of patientshaving known neurological conditions. To perform diagnosis, the projections arecompared to standards, such as one or more characterizing ERP signal vectors fromknown healthy patients, and one or more characterizing ERP signal vectors from patientsknown to have the disorder. The probable presence or absence of the neurologicaldisorder is decided by a weighted vote of the projections, where the weighting is afunction of how closely each projection compares to the respective standards.
Projections can also be used to perform other types of neurological assessment, such astracking a patient's response to a treatment regimen, assessing the treatability of apatient with respect to a particular regimen, determining the effects of a particularregimen, or categorizing a patient in order to create a homogenous group for a clinicaltrial.
申请人:THURIS CORPORATION
代理机构:Sterne, Kessler, Goldstein & Fox PLLC
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